500 mg Testosterone Per Week | Review and Results

Dr. Mike Jansen

Last Updated June 19, 2023

Dr. Mike Jansen

 June 19, 2023

Curious about 500 mg of testosterone per week results?

Do you wonder if 500 mg per week is really the BEST testosterone cycle for experienced users?

Then you’ve come to the right place. In this in-depth guide, we teach you everything you MUST know about 500 mg testosterone cycles, including what kinds of results and side effects you can expect while using these more aggressive dosing protocols.

We also answer your most important questions, including:

  • How fast will I see results with a 500 mg testosterone cycle?
  • Is 500 mg of testosterone per week considered a steroid cycle?
  • How much muscle can I build in 12 weeks with 500 mg of test per week?

…And much more!

Our team of experts has analyzed all of the latest research papers on more aggressive testosterone cycles, so you know you are getting science-based answers for all of your questions.

We even reveal Derek from More Plates More Dates and his personal experience running 500 mg of testosterone per week…

Disclaimer: The contents of Testosterone.org are for informational and educational purposes. We do not provide legal advice. Likewise, we do not provide medical advice, diagnosis, or treatment. Please consult your physician prior to consuming any over-the-counter supplements, like a natural testosterone booster, and/or getting a prescription for a pharmaceutical medication. Your access to Testosterone.org is subject to our full disclaimer and terms of use.

What Is Testosterone? And What Does It Do?

If you’re reading this, then I’m sure you know the importance of maximizing your testosterone levels.

Research shows men with higher testosterone levels experience the following benefits:

  • Increased muscle mass
  • Reduced body fat levels
  • Faster recovery from workouts
  • Improved vascularity
  • Greatest strength in the gym

Men with high T also experience other health benefits, including improved energy levels and sexual performance. Of course, there are benefits to taking higher than normal dosages of testosterone and “going beyond your natural limits.”

More on that in a minute…

For now it’s important to know that low T is becoming increasingly common all around the world [1, 2, 3, 4]. Many older and younger men are suffering from low testosterone levels, and they don’t even know it.

This is unfortunate, as low T causes things like [5, 6, 7]:

  • Reduced muscle mass
  • Reduced confidence and assertiveness
  • Increased recovery time between workouts

…And many other health problems. Research shows the fastest way to boost your testosterone levels is by injecting a testosterone medication at least once per week.

This can be done as part of a testosterone replacement therapy program, or as part of a “steroid cycle” using supra-physiological dosages of testosterone.

And if you’re searching for information on 500 mg testosterone cycles, then we both know which of those camps you fall into…

500 Mg Testosterone

Why Take 500 Mg Of Testosterone Per Week?

Let’s cut to the chase: 500 mg of testosterone per week is considered an aggressive steroid cycle. It is NOT recommended for anyone on TRT, or testosterone replacement therapy.

Most TRT doctors prescribe 100 – 200 mg per week (depending on the patient’s response), as most men are able to maintain blood testosterone levels in the desired 800 – 1,200 ng / dl range using this dosage.

Of course, some men choose to run steroid cycles with 500 mg per week to maximize the anabolic effects of testosterone in the body.

If you are interested in running a steroid cycle with 500 mg of testosterone per week, then keep reading…

So Why Take 500 Mg Of Testosterone Per Week?

500 mg of testosterone per week is considered an aggressive steroid cycle. It may be appropriate for experienced testosterone users who *really* want to push their physical performance to the limit.

Many professional bodybuilders and other athletes choose to run 500 mg of testosterone per week during their “offseason” to build as much muscle mass and strength as possible.

People who run 500 mg of testosterone per week are often looking for dramatic changes in their [10, 11, 12, 13, 14]:

  • Muscle mass
  • Muscle strength
  • Body fat levels
  • Recovery from workouts

Of course, more aggressive steroid cycles also come with greater risk for serious side effects. You have to be extremely careful when running 500 mg of testosterone per week.

Users are encouraged to closely monitor their blood work – particularly their cardiovascular risk factors.

Who Should Take 500 Mg Of Testosterone Per Week?

500 mg testosterone cycles are ONLY recommended for experienced testosterone and steroid users who want to push their performance to the absolute limit.

Aggressive steroid cycles have the potential to shut down your natural testosterone production, and should be followed by a properly planned post-cycle therapy protocol.

500 Mg Of Testosterone Per Week | Results

So what kinds of results can you expect when taking 500 mg of testosterone per week?

500 mg of testosterone per week is considered to be an aggressive steroid cycle. Many Hollywood actors and fitness influencers run 500 mg per week when they are trying to achieve rapid body transformations.

This is also the exact testosterone dosage that Derek from More Plates More Dates used during his first steroid cycle, although he regrets starting at such an aggressive dose.

Studies show users can expect to gain 20-30 pounds of muscle in their first 12 weeks – especially if they are also lifting weights or performing a properly designed resistance training program.

For most users, the effects are immediate and spectacular. Other real-world results seen by users include:

  • Rapid reductions in body fat
  • Extreme increases in vascularity
  • Feeling “invincible” during workouts
  • Rapid improvements in recovery ability

Many men say they feel “invincible” within the first few weeks on this kind of dosage. Indeed, studies show that users taking this kind of dose experience the following benefits:

“Changes in leg press strength, leg power, thigh and quadriceps muscle volumes, hemoglobin, and IGF-I were positively correlated with testosterone concentrations, whereas changes in fat mass and plasma high-density lipoprotein (HDL) cholesterol were negbatively correlated.”

As you might expect, taking 500 mg of testosterone per week results in supra-physiological levels of testosterone. Most studies show users taking this high of a weekly dose achieve total testosterone readings in the 2,000 – 3,000 ng / dl range [15].

Keep in mind, the target range for testosterone levels on TRT is normally 800 – 1,200 ng / dl. This means users are walking around with 2-3x the testosterone levels of men on TRT!

That is the primary reason people see such rapid results with this aggressive of a testosterone dose [16, 17].

500 Mg Testosterone

500 MG Of Testosterone Per Week | Side Effects

What side effects can you expect while cycling 500 mg of testosterone per week?

As you already know, 500 mg of testosterone per week is considered an aggressive steroid cycle. Users taking testosterone dosages this high need to watch out for the following side effects [18, 19, 20]:

  • Internal organ damage
  • Heart disease
  • High blood pressure
  • Atherosclerosis
  • Infertility and low sperm count

One of the most common side effects is cardiovascular disease, including damage to the heart or blood vessels. This is caused by the elevated androgen levels in the body.

If you are interested in running steroid-level doses of testosterone, then you MUST research these side effects in greater depth, and know how to monitor your blood work.

How To Inject 500 Mg Of Testosterone Per Week

You’ve done your research, and you are finally ready to start taking 500 mg of testosterone per week… so how do you actually perform the testosterone injections?

Let’s start by discussing the optimal injection frequency, followed by the actual steps for injecting testosterone.
500 mg of testosterone per week is considered an aggressive steroid cycle. To minimize the chances for side effects, we recommend injecting at least 2-3 days per week. For example:

  • Option #1: 250 mg two days per week
  • Option #2: 167 mg three days per week

Smaller, more frequent injections are encouraged because they will help you maintain stable blood testosterone levels during the week [21].

If you try injecting once per week (or less), then your testosterone levels will fluctuate significantly throughout the week, which increases your risk for side effects like gynecomastia.

Now let’s look at the actual steps for injecting testosterone:

  • Step #1: Wash your hands – this is absolutely crucial for preventing infections while injecting.
  • Step #2: Draw up a dose – this depends on how frequently you are injecting. For example, if you are injecting twice per week, then you would load up the syringe with 250 mg of testosterone.
  • Step #3: Aspirate the syringe – this is essential for ensuring there are no air bubbles in the syringe when you inject the testosterone.
  • Step #4: Prepare the injection site – this involves wiping the target area with a sterile alcohol pad.
  • Step #5: Inject the testosterone dose – hold the syringe at a 90 degree angle to the application site, plunge the syringe into the flesh, pull back slightly, and depress the plunger.
  • Step #6: Remove the needle – after you are done, carefully pull the syringe out of the muscle / skin.

Most experienced testosterone users taking 500 mg of testosterone per week prefer injecting into the glutes, deltoids, or any other large muscle group.

Intra-muscular injections are preferred over subcutaneous injections, as they have a larger body of research backing their overall efficacy [22, 23].

500 Mg Testosterone

How To Buy Testosterone Online | MUST Read

You’re ready to start your first 500 mg testosterone cycle.

There’s just one problem… how do you actually buy testosterone online? And is it even legal to buy testosterone over the internet?

The truth is buying testosterone online without a doctor’s prescription is illegal in most parts of the world, including the United States, Canada, and most of Europe.

Of course, we do NOT recommend buying testosterone illegally. The other issue with buying testosterone over the internet is many online vendors use inferior quality products that are filled with cheap fillers [24].

In our experience, the best solution for most men is to get their testosterone through an online TRT clinic. Here are some of the advantages of this option:

  • You get a pharmaceutical-grade testosterone medication
  • It is 100% legal, as they give you a testosterone prescription
  • Your doctor monitors all of your bloodwork for you
  • They customize your treatment plan to maximize your results

Working with a doctor is also helpful for avoiding nasty side effects like gynecomastia and cardiovascular disease. Remember, most people who take testosterone on their own without any supervision end up experiencing nasty side effects [25, 26, 27].

If you are serious about getting results as quickly as possible, then working with a reliable online TRT provider is the way to go.

Fortunately, it’s very easy to get started with an online TRT clinic. All you have to do is follow these steps:

  • Step #1: Fill out an online “low T” questionnaire and go over the results with your doctor.
  • Step #2: Perform a blood test at a local facility to measure your exact testosterone levels.
  • Step #3: Go over the results with your doctor, get your customized TRT treatment plan, and have your prescription testosterone medication shipped straight to your door!

Almost every online TRT clinic uses a similar 3-step process, which makes getting your hands on a pharmaceutical grade testosterone product extremely easy.

As an added bonus, your online TRT clinic that accepts insurance will ship your testosterone medication straight to your door. This means you can get your hands on a testosterone medication without ever having to visit a traditional doctor’s office!

If you are ready to get started with our preferred online TRT provider, then click on the following link:

Sign up for TRT today with our top-rated USA doctors...

Best Natural Test Boosters | That Actually Work

You may have heard about testosterone boosting supplements before… you know, those pills you take to magically boost your testosterone levels by hundreds of points.

But are these supplements actually effective, and are they a good replacement for traditional testosterone injections?

Let’s look at the facts before jumping to any conclusions.

The truth is most over-the-counter testosterone boosters are NOT safe or effective. They are usually filled with cheap ingredients that do absolutely nothing for improving your total testosterone levels. Even worse, these ingredients rarely have scientific studies backing their safety and efficacy.

Here are the facts that you MUST know about traditional testosterone boosting supplements:

  • They have little to no research backing them [28]
  • They may have dangerous long-term side effects [29]
  • They do a very poor job of actually raising your testosterone levels [30]

Why would anyone waste their hard-earned money on such products? Your guess is as good as mine!

Fortunately, our team at Testosterone.org was able to find one product that actually delivers on its promises: Maximus Tribe.

The thing that sets Maximus Tribe apart from other so-called testosterone boosting supplements is it actually produces results in the real world. Maximus Tribe uses a new ingredient called enclomiphine, which is really just a concentrated and purified version of the original drug clomid.

Enclomiphine works by “tricking” your body into producing more total testosterone. It does this by making your body think you have a testosterone deficiency, so it ramps up testosterone production in the testes.

Research shows that men who use Maximus Tribe see their total testosterone increase by as much as 200 – 300 points [31, 32, 33]!

This is an incredible result for an over-the-counter drug. If you are ready to get started with Maximus Tribe, then here is where you can learn more:


Is 500 Mg Of Testosterone Per Week Enough? Verdict

So what’s the verdict… what kinds of results can you expect while injecting 500 mg of testosterone per week?

Here’s the truth: 500 mg of testosterone per week is considered an AGGRESSIVE steroid cycle. It produces serious results in terms of size and strength gains, as well as improved recovery ability and overall body composition improvements.

Many users are able to gain 15-20+ pounds of pure muscle mass in their first 12 week steroid cycle of 500 mg of testosterone per week!

Of course, there is a greater risk for side effects with this aggressive weekly testosterone dosage. We recommend working with an experienced online TRT clinic, as they will monitor your bloodwork for you and help you manage any potential side effects.

Of course, you can also take a powerful over-the-counter testosterone boosting product like Maximus Tribe if you are just interested in boosting your total testosterone levels by 200-300 points.


  1. Millar AC, Lau ANC, Tomlinson G, Kraguljac A, Simel DL, Detsky AS, Lipscombe LL. Predicting low testosterone in aging men: a systematic review. CMAJ. 2016 Sep 20;188(13):E321-E330. doi: 10.1503/cmaj.150262. Epub 2016 Jun 20. PMID: 27325129; PMCID: PMC5026531.
  2. Liu YJ, Shen XB, Yu N, et al. Prevalence of late-onset hypogonadism among middle-aged and elderly males in China: results from a national survey. Asian J Androl. 2021;23(2):170-177. doi:10.4103/aja.aja_59_20
  3. Braga PC, Pereira SC, Ribeiro JC, Sousa M, Monteiro MP, Oliveira PF, Alves MG. Late-onset hypogonadism and lifestyle-related metabolic disorders. Andrology. 2020 Nov;8(6):1530-1538. doi: 10.1111/andr.12765. Epub 2020 Feb 16. PMID: 31991053.
  4. Cohen J, Nassau DE, Patel P, Ramasamy R. Low Testosterone in Adolescents & Young Adults [published correction appears in Front Endocrinol (Lausanne). 2020 Jul 14;11:449]. Front Endocrinol (Lausanne). 2020;10:916. Published 2020 Jan 10. doi:10.3389/fendo.2019.00916
  5. Wong R.M.Y., Wong H., Zhang N., Chow S.K.H., Chau W.W., Wang J., Chim Y.N., Leung K.S., Cheung W.H. The relationship between sarcopenia and fragility fracture-a systematic review. Osteoporos. Int. 2019;30:541–553. doi: 10.1007/s00198-018-04828-0. – DOI – PubMed
  6. Naoki Harada, Role of androgens in energy metabolism affecting on body composition, metabolic syndrome, type 2 diabetes, cardiovascular disease, and longevity: lessons from a meta-analysis and rodent studies, Bioscience, Biotechnology, and Biochemistry, Volume 82, Issue 10, 3 October 2018, Pages 1667–1682, https://doi.org/10.1080/09168451.2018.1490172
  7. Liu ZY, Yang Y, Wen CY, Rong LM. Serum Osteocalcin and Testosterone Concentrations in Adult Males with or without Primary Osteoporosis: A Meta-Analysis. Biomed Res Int. 2017;2017:9892048. doi:10.1155/2017/9892048
  8. Bhasin S, Zhang A, Coviello A, Jasuja R, Ulloor J, Singh R, Vesper H, Vasan RS. The impact of assay quality and reference ranges on clinical decision making in the diagnosis of androgen disorders. Steroids. 2008 Dec 12;73(13):1311-7. doi: 10.1016/j.steroids.2008.07.003. Epub 2008 Jul 17. PMID: 18687348.
  9. Solberg HE, PetitClerc C. Approved recommendation (1988) on the theory of reference values. Part 3. Preparation of individuals and collection of specimens for the production of reference values. Clin Chim Acta. 1988 Oct 31;177(3):S3-11. doi: 10.1016/0009-8981(88)90074-5. PMID: 3233768.
  10. Al-Zoubi RM, Yassin AA, Alwani M, Al-Qudimat A, Aboumarzouk OM, Zarour A, Al Ansari A. A systematic review on the latest developments in testosterone therapy: Innovations, advances, and paradigm shifts. Arab J Urol. 2021 Aug 8;19(3):370-375. doi: 10.1080/2090598X.2021.1959260. PMID: 34552788; PMCID: PMC8451690.
  11. Kim SH, Park JJ, Kim KH, Yang HJ, Kim DS, Lee CH, Jeon YS, Shim SR, Kim JH. Efficacy of testosterone replacement therapy for treating metabolic disturbances in late-onset hypogonadism: a systematic review and meta-analysis. Int Urol Nephrol. 2021 Sep;53(9):1733-1746. doi: 10.1007/s11255-021-02876-w. Epub 2021 Jun 5. PMID: 34089171.
  12. Lunenfeld B, Mskhalaya G, Zitzmann M, Corona G, Arver S, Kalinchenko S, Tishova Y, Morgentaler A. Recommendations on the diagnosis, treatment and monitoring of testosterone deficiency in men. Aging Male. 2021 Dec;24(1):119-138. doi: 10.1080/13685538.2021.1962840. PMID: 34396893.
  13. Chegeni, R., Pallesen, S., McVeigh, J. et al. Anabolic-androgenic steroid administration increases self-reported aggression in healthy males: a systematic review and meta-analysis of experimental studies. Psychopharmacology 238, 1911–1922 (2021). https://doi.org/10.1007/s00213-021-05818-7
  14. Albano GD, Amico F, Cocimano G, Liberto A, Maglietta F, Esposito M, Rosi GL, Di Nunno N, Salerno M, Montana A. Adverse Effects of Anabolic-Androgenic Steroids: A Literature Review. Healthcare (Basel). 2021 Jan 19;9(1):97. doi: 10.3390/healthcare9010097. PMID: 33477800; PMCID: PMC7832337.
  15. Bhasin S, Woodhouse L, Casaburi R, Singh AB, Bhasin D, Berman N, Chen X, Yarasheski KE, Magliano L, Dzekov C, Dzekov J, Bross R, Phillips J, Sinha-Hikim I, Shen R, Storer TW. Testosterone dose-response relationships in healthy young men. Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1172-81. doi: 10.1152/ajpendo.2001.281.6.E1172. PMID: 11701431.
  16. Andrews MA, Magee CD, Combest TM, Allard RJ, Douglas KM. Physical Effects of Anabolic-androgenic Steroids in Healthy Exercising Adults: A Systematic Review and Meta-analysis. Curr Sports Med Rep. 2018 Jul;17(7):232-241. doi: 10.1249/JSR.0000000000000500. PMID: 29994823.
  17. Bhasin S, Woodhouse L, Casaburi R, Singh AB, Bhasin D, Berman N, Chen X, Yarasheski KE, Magliano L, Dzekov C, Dzekov J, Bross R, Phillips J, Sinha-Hikim I, Shen R, Storer TW. Testosterone dose-response relationships in healthy young men. Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1172-81. doi: 10.1152/ajpendo.2001.281.6.E1172. PMID: 11701431.
  18. van Amsterdam J, Opperhuizen A, Hartgens F. Adverse health effects of anabolic-androgenic steroids. Regul Toxicol Pharmacol. 2010 Jun;57(1):117-23. doi: 10.1016/j.yrtph.2010.02.001. Epub 2010 Feb 12. PMID: 20153798.
  19. Horwitz H, Andersen JT, Dalhoff KP. Health consequences of androgenic anabolic steroid use. J Intern Med. 2019 Mar;285(3):333-340. doi: 10.1111/joim.12850. Epub 2018 Nov 20. PMID: 30460728.
  20. Hoffman JR, Ratamess NA. Medical issues associated with anabolic steroid use: are they exaggerated? J Sports Sci Med. 2006 Jun 1;5(2):182-93. PMID: 24259990; PMCID: PMC3827559.
  21. Borst SE, Yarrow JF. Injection of testosterone may be safer and more effective than transdermal administration for combating loss of muscle and bone in older men. Am J Physiol Endocrinol Metab. 2015 Jun 15;308(12):E1035-42. doi: 10.1152/ajpendo.00111.2015. Epub 2015 Apr 21. PMID: 25898953; PMCID: PMC6189635.
  22. Choi EJ, Xu P, Barham D, El-Khatib FM, Yafi FA, Kavoussi PK. Comparison of Outcomes for Hypogonadal Men Treated with Intramuscular Testosterone Cypionate versus Subcutaneous Testosterone Enanthate. J Urol. 2022 Mar;207(3):677-683. doi: 10.1097/JU.0000000000002301. Epub 2021 Oct 25. PMID: 34694927.
  23. “Subcutaneous vs. Intramuscular Testosterone – Full Text View.” Full Text View – ClinicalTrials.gov, https://clinicaltrials.gov/ct2/show/NCT03091348.
  24. “1 In 10 Medical Products in Developing Countries Is Substandard or Falsified.” World Health Organization, World Health Organization, https://www.who.int/news-room/detail/28-11-2017-1-in-10-medical-products-in-developing-countries-is-substandard-or-falsified.
  25. Kohn TP, Mata DA, Ramasamy R, Lipshultz LI. Effects of Testosterone Replacement Therapy on Lower Urinary Tract Symptoms: A Systematic Review and Meta-analysis. Eur Urol. 2016 Jun;69(6):1083-90. doi: 10.1016/j.eururo.2016.01.043. Epub 2016 Feb 11. PMID: 26874809.
  26. Jia H, Sullivan CT, McCoy SC, Yarrow JF, Morrow M, Borst SE. Review of health risks of low testosterone and testosterone administration. World J Clin Cases. 2015 Apr 16;3(4):338-44. doi: 10.12998/wjcc.v3.i4.338. PMID: 25879005; PMCID: PMC4391003.
  27. Corona G, Rastrelli G, Di Pasquale G, Sforza A, Mannucci E, Maggi M. Endogenous Testosterone Levels and Cardiovascular Risk: Meta-Analysis of Observational Studies. J Sex Med. 2018 Sep;15(9):1260-1271. doi: 10.1016/j.jsxm.2018.06.012. Epub 2018 Aug 23. PMID: 30145097.
  28. “Are Testosterone-Boosting Supplements Effective?: Keck School of Medicine of USC.” Keck School of Medicine of USC | Leaders in Medical Education, Research and Patient Care, 26 Jan. 2022, https://keck.usc.edu/are-testosterone-boosting-supplements-effective-not-likely-says-new-study/.
  29. Almaiman AA. Effect of testosterone boosters on body functions: Case report. Int J Health Sci (Qassim). 2018 Mar-Apr;12(2):86-90. PMID: 29599700; PMCID: PMC5870326.
  30. Renner, Ben. “Most Testosterone Supplements Nothing but Bull: Pills Will Leave You and Your Wallet Limp.” Study Finds, 14 July 2022, https://studyfinds.org/testosterone-supplements-t-boosters-dont-work/.
  31. McCullough A. Alternatives to testosterone replacement: testosterone restoration. Asian J Androl. 2015;17(2):201-5.
  32. Krzastek SC, Sharma D, Abdullah N, et al. Long-Term Safety and Efficacy of Clomiphene Citrate for the Treatment of Hypogonadism. J Urol. 2019;202(5):1029-35.
  33. Katz DJ, Nabulsi O, Tal R, Mulhall JP. Outcomes of clomiphene citrate treatment in young hypogonadal men. BJU Int. 2012;110(4):573-8.
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