Huge Sapogenix | Review of Benefits, Side Effects, and Clinical Trials

Dr. Mike Jansen

Last Updated September 28, 2022

Dr. Mike Jansen

 September 28, 2022

Curious about Huge Supplements Sapogenix?

Do you wonder if Huge Supplement Sapogenix is the world’s leading “legal steroid alternative,” or just another marketing scam?

Then you’ve come to the right place. In this comprehensive guide, we detail everything you need to know about the Sapogenix, including how to use this laxogenin-based product for best results.

We also answer your most important laxogenin questions, including:

  • Is laxogenin safe?
  • How long can I use laxogenin for?
  • What kind of results can I expect with laxogenin?

…And so much more!

Our team has reviewed dozens of reviews from verified Sapogenix customers, so you’re getting science-based answers on how this product performs in the real-world.

By the end of this helpful guide, you will be more than ready to add Huge Supplements Sapogenix to your current supplement stack.

Now let’s get started!

Disclaimer: The contents of are for informational and educational purposes. We do not provide legal advice. Likewise, we do not provide medical advice, diagnosis, or treatment. Please consult your physician prior to consuming any over-the-counter supplements, like a natural testosterone booster, and/or getting a prescription for a pharmaceutical medication. Your access to is subject to our full disclaimer and terms of use.

What is Laxogenin?

Laxogenin is a natural plant steroid that is found in many different plant species, including Smilax Sieboldii and many others.

Don’t worry – laxogenin is completely different from anabolic steroids and other illegal drugs.
It belongs to a class of plant steroids called “brassinosteroids,” and it works by increasing the rate of protein synthesis in plant cells (1, 2).

Many natural plant steroids like ecdysterone and turkesterone have been shown to increase muscle protein synthesis in human and animal studies (3, 4, 5, 6). Based on these results, some people believe that brassinosteroids like laxogenin may produce similar results in humans.

So far there are very few, if any, human or animal studies performed on laxogenin (7, 8).

However, that doesn’t mean you should ignore this popular “legal steroid alternative.” Many real-world users are reporting excellent results from laxogenin, so it may deserve a place in your supplement program.

So how does laxogenin work?

Laxogenin has a very similar chemical structure to testosterone. In plants, laxogenin works by directly increasing the rate of protein synthesis in developing cells.

Other natural plant steroids like ecdysterone have been shown to increase the rate of protein synthesis in human muscle cells by as much as 20%, and some people believe that laxogenin should produce similar effects.

Don’t worry – laxogenin does NOT impact your hormone levels, such as your total testosterone.

Instead, it increases muscle protein synthesis without causing any change in your hormones.

This makes it a great choice for someone who wants to speed up their progress in the gym, but without using anabolic steroids and other dangerous or illegal drugs.

Huge Sapogenix Review

What is Huge Sapogenix?

Huge supplements is one of the most trusted supplement companies in the fitness industry.

Huge Supplements was founded in 2019 with a single goal: to produce the highest quality supplements available anywhere in the world.

Based on our research, Huge Supplements is the real deal.

Here are a few of the reasons we recommend Huge Supplements over every other laxogenin brand:

  • Manufacture products in the United States
  • Produce products in FDA-regulated facilities
  • All products have 3rd-party quality tests
  • Fast, reliable shipping to the US and abroad
  • The best customer service in the industry

Of course, the most important factor with any supplement company is the quality of their products.

In other words, do they use the highest quality ingredients, and do they submit their products through rigorous 3rd-party testing?

This is where Huge Supplements really shines as a company.

They produce all of their products right here in the United States under FDA-regulated facilities. They only use the highest quality ingredients in their products, and unlike their competitors, they never use cheap fillers to increase their profits.

Most importantly, thousands of users all over the world are getting great results with Huge Supplements products – including their flagship laxogenin product, Sapogenix.

Laxogenin Benefits

If you are reading this article, then I’m sure you’ve heard of the breakthrough supplement called laxogenin. Thousands of users are reporting the best gains of their entire life while using this natural plant steroid.

But what kinds of benefits can you expect while cycling laxogenin?

Based on our research, most users experience the following benefits while using laxogenin (9, 10, 11, 12, 13):

  • Faster size and strength gains
  • Improved recovery ability
  • Enhanced muscular endurance
  • Improved exercise performance

Let’s take a closer look at each of these benefits.

The main benefit you can expect during your first laxogenin cycle is significantly faster size and strength gains. Many users gain up to 5-10 pounds during their first 6-12 week cycle, while reporting looking visibly bigger and more “full.”

Another huge benefit is improved recovery ability.

Based on anecdotal evidence, most people recover faster from intense workouts while using laxogenin. Many users are able to train longer or more frequently while using this product, without having to worry about overtraining.

Of course, more research is required to identify all of the possible benefits of laxogenin.

Huge Sapogenix Review

Laxogenin Side Effects

Most people do not experience any side effects while cycling laxogenin. However, that does not mean there are no side effects whatsoever.

Here are some of the most common side effects reported while cycling laxogenin:

  • Nausea or upset stomach
  • Minor headaches
  • Heavy Urination

Let’s take a closer look at each of these side effects.

The most common side effect people experience while cycling laxogenin is nausea or an upset stomach. This is often caused by taking more than our recommended dose of 100 – 200 mg per day, or from taking laxogenin on an empty stomach.

If you do experience one of these symptoms, then an easy solution is taking no more than 100 mg of laxogenin at a time, and consuming it with a whole food meal.

This will increase absorption of the product and reduce your symptoms.

Other possible side effects include minor headaches or heavy urination.

At this time, no serious long-term side effects have been reported while using laxogenin. This makes laxogenin one of the safest “legal steroid alternatives” on the market today.

Huge Sapogenix Bodybuilding Supplement | Review

There are a lot of great laxogenin supplements on the market today.

So how do you tell the difference between an average laxogenin product, and a premium one?

The most important thing to consider when choosing a laxogenin product is the company.

  • Are you purchasing from a trusted brand that makes their own products in regulated facilities?
  • Do they use the highest quality ingredients, or cheap fillers to increase their profits?

Based on our research, purchasing your laxogenin supplement from Huge Supplements is the obvious choice.

Huge Supplements makes 2 different laxogenin based products: Sapogenix and Annihilate.

Both of these are great options. However, if you are serious about getting results fast, then we recommend Huge Supplements Sapogenix.

Huge Supplements Sapogenix

  • Servings: 60
  • Amount per serving: 250 mg

Sapogenix is different from other laxogenin products because it contains a proprietary blend of several different natural plant steroids.

Laxogenin is the primary ingredient, but also contains 6-keto-disogenin, spirostanol sapogenins, furastanolic sapogenins, and many others ingredients.

Huge Supplements says that these ingredients work synergistically to increase protein synthesis higher than pure laxogenin products.

This means faster gains in the gym, and more lean muscle tissue!

Here are some of the other reasons we recommend Huge Supplements Sapogenix:

  • 250 mg of laxogenin and other natural plant steroids per capsule
  • Patented cyclosome technology for maximum absorption
  • The highest quality ingredients available anywhere in the world
  • Produced by a company you can trust – Huge Supplements
  • Ultra-fast shipping and great customer service

Of course, none of this matters if the product doesn’t produce results in the real world.

Based on our research, Huge Supplements Sapogenix is producing faster results than any other laxogenin-based product on the market.

Here is what verified customers are saying about this product:

“Awesome stuff! Did 638lbs leg press for pause reps of 6! 5’11” 163lb, I could’ve done like another plate wtf! Before this stuff could only do 545. No sense!” – Cody C

“Been taking for four weeks my bench went from 160 to 200 great strength improvement as well as being able to work harder and heavier in the gym.” – Nick L

“Strength is through the roof only taken for 2 weeks. I can’t tell about size. Still weighing 255 but I am seemingly more vascular.” – Kevin R

As you can see, most users are getting phenomenal results while taking this product. Almost everyone reports screaming fast strength gains and improved recovery ability.

If you are ready to take your physique to the next level, then picking up a bottle of Huge Supplements Sapogenix is the obvious choice.

Order Laxogenin from our top-rated USA vendor...

Where to Buy Huge Sapogenix?

By now you’re probably ready to get started with your first cycle of Huge Supplements Sapogenix.

But where should you purchase this product?

Based on our research, you should NOT purchase Huge Supplements Annihilate from Amazon. Most users say that amazon swapped out Sapogenix for an inferior quality product. The new product does NOT work the same as the original formula.

Instead, we recommend purchasing directly from the Huge Supplements website.

That way, you know you are getting the authentic product manufactured directly by Huge Supplements themselves.

Order Laxogenin from our top-rated USA vendor...

Laxogenin Dosage

By now you’re probably wondering how much laxogenin you should take each day.

Is more laxogenin better, or is there a limit to how much you can actually take?

Based on our research, the optimal laxogenin dose is 100 – 200 mg per day for 6-12 weeks. This dosing protocol is high enough to deliver fantastic results, while low enough to minimize any unwanted side effects.

We recommend starting with 100 mg per day, and monitoring your results. If you do not experience any side effects, then you can increase to 200 mg spread out over 2 equal doses.

This is the “sweet spot” where most people see the fastest progress.

Most users choose to “cycle” laxogenin for up to 12 weeks at a time. They use laxogenin anywhere from 6-12 weeks in a row, followed by a 4-8 week break from the product.

This is not strictly necessary, as laxogenin does not impact your hormone levels, and will not require a PCT.

However, it can be a good idea to minimize potential side effects. After all, laxogenin is a relatively new supplement, and more research is required to pinpoint the optimal dosing protocol.

Laxogenin Cycle

Laxogenin is technically not an anabolic steroid. It does not impact your hormone levels, such as your total testosterone, and it does not require a PCT.

So why do so many people choose to “cycle” laxogenin for a few weeks at a time?

The truth is, most people choose to cycle laxogenin for safety reasons. The most popular laxogenin cycle is 100 – 200 mg per day for 6-12 weeks, followed by a 4-8 week break from the product.

People choose to take a break from laxogenin every 2-3 months because the product is new, and we don’t know if it has any long-term side effects. Cycling laxogenin is a smart way to avoid long-term issues, such as liver toxicity or other complications.

Of course, we aren’t saying that laxogenin is dangerous.

So far, no one has reported any serious long-term side effects, and the available research studies seem to indicate that laxogenin is extremely safe. However, cycling the product is probably the smart move.

Don’t worry – you should see substantial progress during your first laxogenin cycle, and you won’t lose your gains during the off period.

Huge Sapogenix Review

Is Laxogenin a Steroid?

You might be wondering if laxogenin is an anabolic steroid. After all, can a natural non-hormonal product like laxogenin really produce steroid-like gains?

Fortunately, the answer is simple: no, laxogenin is NOT a steroid.

It is does not cause any changes to your hormone levels, such as your total testosterone, and it does not have any of the side effects associated with anabolic steroids.

Instead, laxogenin is a natural non-hormonal product that you can use to build muscle mass and strength. It is especially effective for natural bodybuilders and other drug-free athletes who want to get an edge over their competition.

Does Laxogenin Suppress Testosterone?

Laxogenin is sometimes advertised as a “legal steroid alternative.”

This is a very appropriate name, as unlike anabolic steroids, laxogenin does NOT suppress your natural testosterone production.

In fact, laxogenin has no impact on your testosterone levels at all! This means you do not need to run a PCT, or post-cycle therapy, after your first laxogenin cycle.

Based on our research, laxogenin is a perfect choice for the “natty” athlete who wants to speed up their progress in the gym.

You may have some people asking you if you are on steroids – especially if you run a proper 6-12 week cycle of laxogenin. However, you can rest easy knowing that this product does NOT suppress your testosterone levels at all.

Huge Sapogenix Review

Does Laxogenin Work?

By now you’re probably wondering if laxogenin actually works.

Is it really as effective as people say it is?

The truth is there are no human studies on laxogenin, so it’s hard to give a science-based answer to this question. However, there are thousands of positive reviews on laxogenin, which shows that this product works extremely well in the real-world.

Many verified customers say they gained as much as 5-10 pounds of lean muscle mass in 6-12 weeks during their first laxogenin cycle!

Others say they had screaming fast strength gains while using this product, and they felt more “pumped” and “full” throughout the day.

More research is required to figure out exactly how effective laxogenin is for building muscle mass and strength. However, the real-world results show that laxogenin works extremely well for many people.

Huge Sapogenix | Review

In conclusion…

Huge Supplements Sapogenix is the premier laxogenin product in the world today.

We like the Huge Supplements brand because they manufacture all of their supplements right here in the United States.

All of their products are produced in FDA-regulated facilities, which means they use nothing but the highest quality ingredients.

Each capsule of Huge Supplements Sapogenix contains 250 mg of laxogenin plus several other “legal plant steroids.” These ingredients work synergistically to maximize your size and strength gains, which is exactly what you want!

Laxogenin is still a new supplement, and more research is required to fully understand its impact on humans.

However, the anecdotal evidence surrounding laxogenin is extremely promising, as many people are getting the best gains of their entire life while using it.

So what are you waiting for?

Pick up a bottle of Huge Supplements Sapogenix today and take your physique to the next level!


  1.  Bishop GJ, Koncz C. Brassinosteroids and plant steroid hormone signaling. Plant Cell. 2002;14 Suppl(Suppl):S97-S110. doi:10.1105/tpc.001461
  2.  Wang Q, Xu J, Liu X, Gong W, Zhang C. Synthesis of brassinosteroids analogues from laxogenin and their plant growth promotion. Nat Prod Res. 2015;29(2):149-57. doi: 10.1080/14786419.2014.968151. Epub 2014 Oct 14. PMID: 25311045.
  3.  Isenmann E, Ambrosio G, Joseph JF, Mazzarino M, de la Torre X, Zimmer P, Kazlauskas R, Goebel C, Botrè F, Diel P, Parr MK. Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans. Arch Toxicol. 2019 Jul;93(7):1807-1816. doi: 10.1007/s00204-019-02490-x. Epub 2019 May 23. PMID: 31123801.
  4.  Parr MK, Botrè F, Naß A, Hengevoss J, Diel P, Wolber G. Ecdysteroids: A novel class of anabolic agents?. Biol Sport. 2015;32(2):169-173. doi:10.5604/20831862.1144420
  5.  Syrov VN, Kurmukov AG. Ob anabolicheskikh svostvakh fitoekdizona turkesterona i tetraatsetata turkesterona v opytakh na samtsakh krys [The anabolic properties of turkesterone phytoecdysone and turkesterone tetraacetate in experiments on male rats]. Probl Endokrinol (Mosk). 1976 May-Jun;22(3):107-12. Russian. PMID: 935080.
  6.  Dinan L, Bourne P, Whiting P, Tsitsekli A, Saatov Z, Dhadialla TS, Hormann RE, Lafont R, Coll J. Synthesis and biological activities of turkesterone 11alpha-acyl derivatives. J Insect Sci. 2003;3:6. doi: 10.1093/jis/3.1.6. Epub 2003 Feb 24. PMID: 15841223; PMCID: PMC524646.
  7.  Esposito D, Komarnytsky S, Shapses S, Raskin I. Anabolic effect of plant brassinosteroid. FASEB J. 2011;25(10):3708-3719. doi:10.1096/fj.11-181271
  8.  Esposito D, Rathinasabapathy T, Poulev A, Komarnytsky S, Raskin I. Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells. J Med Chem. 2011;54(12):4057-4066. doi:10.1021/jm200028h
  9.  Hajduch E, Alessi DR, Hemmings BA, Hundal HS. Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells. Diabetes. 1998 Jul;47(7):1006-13. doi: 10.2337/diabetes.47.7.1006. PMID: 9648821.
  10.  Rommel C, Bodine SC, Clarke BA, Rossman R, Nunez L, Stitt TN, Yancopoulos GD, Glass DJ. Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways. Nat Cell Biol. 2001 Nov;3(11):1009-13. doi: 10.1038/ncb1101-1009. PMID: 11715022.
  11.  Hursel R, Westerterp-Plantenga MS. Thermogenic ingredients and body weight regulation. Int J Obes (Lond). 2010 Apr;34(4):659-69. doi: 10.1038/ijo.2009.299. Epub 2010 Feb 9. PMID: 20142827.
  12.  Zhang YW, Morita I, Zhang L, Shao G, Yao XS, Murota S. Screening of anti-hypoxia/reoxygenation agents by an in vitro method. Part 2: Inhibition of tyrosine kinase activation prevented hypoxia/reoxygenation-induced injury in endothelial gap junctional intercellular communication. Planta Med. 2000 Mar;66(2):119-23. doi: 10.1055/s-2000-11126. PMID: 10763583.
  13.  Zhang YW, Morita I, Shao G, Yao XS, Murota S. Screening of anti-hypoxia/reoxygenation agents by an in vitro model. Part 1: Natural inhibitors for protein tyrosine kinase activated by hypoxia/reoxygenation in cultured human umbilical vein endothelial cells. Planta Med. 2000 Mar;66(2):114-8. doi: 10.1055/s-2000-11128. PMID: 10763582.
Table of Contents
    Add a header to begin generating the table of contents